Pediatric Age-Specific SIRS Criteria

Age

HR (high)

HR (low)

Resp Rate

Min Systolic

Birth – 1wk

>180

<100

>60

60

1wk – 1mo

>180

<100

>50

75

1mo – 2yrs

>180

<90

>35

75

2 – 5yrs

>140

N/A

>30

75

6 – 12yrs

>130

N/A

>20

83

>12yrs

>110

N/A

>20

90


Severe Pediatric Sepsis

Includes SIRS and two or more of the following signs of hypo-perfusion or organ dysfunction that is new and not explained by other known etiology of organ dysfunction:

  • Proven need for >50% FiO2 to maintain saturation ≥ 92%
  • Need for non-elective invasive or noninvasive mechanical ventilation
  • Glasgow Coma Score ≤11 
  • Acute change in mental status with a decrease in Glasgow Coma Score ≥3 points from abnormal baseline

In Hospital Criteria

  • Unexplained metabolic acidosis: base deficit > 5.0 mEq/L
  • Increased arterial lactate > times upper limit of normal
  • Oliguric: urine output <0.5 mL/kg/hr
  • Core to peripheral temperature gap > 3°C
  • PAO2/FIO2 <300 in absence of cyanotic heart disease or preexisting lung disease
  • PaCO2 >65 torr or 20 mmHg over baseline PaCO2


References

Dellinger, R. Phillip et al, Surviving Sepsis Campaign: International Guidelines for Management of Severe Sepsis and Septic Shock: 2012. Critical Care Medicine, Feb.2013, Vol.41, No2.

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