Pediatric Age-Specific SIRS Criteria
Age |
HR (high) |
HR (low) |
Resp Rate |
Min Systolic |
Birth – 1wk |
>180 |
<100 |
>60 |
60 |
1wk – 1mo |
>180 |
<100 |
>50 |
75 |
1mo – 2yrs |
>180 |
<90 |
>35 |
75 |
2 – 5yrs |
>140 |
N/A |
>30 |
75 |
6 – 12yrs |
>130 |
N/A |
>20 |
83 |
>12yrs |
>110 |
N/A |
>20 |
90 |
Severe Pediatric Sepsis
Includes SIRS and two or more of the following signs of hypo-perfusion or organ dysfunction that is new and not explained by other known etiology of organ dysfunction:
- Proven need for >50% FiO2 to maintain saturation ≥ 92%
- Need for non-elective invasive or noninvasive mechanical ventilation
- Glasgow Coma Score ≤11
- Acute change in mental status with a decrease in Glasgow Coma Score ≥3 points from abnormal baseline
In Hospital Criteria
- Unexplained metabolic acidosis: base deficit > 5.0 mEq/L
- Increased arterial lactate > times upper limit of normal
- Oliguric: urine output <0.5 mL/kg/hr
- Core to peripheral temperature gap > 3°C
- PAO2/FIO2 <300 in absence of cyanotic heart disease or preexisting lung disease
- PaCO2 >65 torr or 20 mmHg over baseline PaCO2
References
Dellinger, R. Phillip et al, Surviving Sepsis Campaign: International Guidelines for Management of Severe Sepsis and Septic Shock: 2012. Critical Care Medicine, Feb.2013, Vol.41, No2.