- Aspirin also falls under many other functional classifications
- Inhibits the formation of thromboxane A2 which is a potent platelet aggregate and vasoconstrictor.
- Onset - 1 hour, 20 minutes if chewed
- Peak - 1 to 2 hours
- Duration - 4 to 6 hours; platelet inhibitory effects last the lifetime of the platelet (~10 days)
- Chest pain or atypical symptoms consistent with cardiac ischemia/AMI.
- Allergy to aspirin or other non-steroidal anti-inflammatory (NSAIDS) agents. This includes many non-aspirin/non-Tylenol pain relievers such as Advil.
- Asthma (see special notes).
- Recent head injury, stroke or acute bleeding (significant) of any kind.
- Pediatric patients with viral symptoms.
- Recent internal bleeding (within last 3 months).
- Known bleeding diseases.
- Patients currently taking anticoagulant agent(s).
- Recent surgery.
- Possibility of pregnancy.
- 160 mg
- Have the patient chew ASA before swallowing.
- Contraindicated in pediatric patients with viral illness. (See notes below)
- Chest pain in children is unlikely to be ischemic in nature therefore ASA not indicated unless rare specific ischemic cardiac history.
ASA has been linked to Reye’s syndrome in children with a viral history such as chicken pox, or influenza.
Asthma – contraindicated in patients who have experienced an exacerbation of their asthma after taking ASA.