Increases myocardial contractility and ventricular automaticity.
- Excretion: feces (80%) and urine (20%)
- Cardiac arrest due to suspected hyperkalemia (DKA, renal failure).
- Suspected hyperkalemia with cardiovascular toxicity (wide QRS, peaked T waves or hemodynamic instability).
- Calcium channel blocker overdose with symptomatic bradycardia or hemodynamic instability.
- Hypersensitivity to calcium chloride
- Primary or secondary hypercalcemia
- Extravasation causes tissue necrosis.
- IV use only; not to be administered IM, subcutaneously or intramyocardially: results in severe tissue necrosis.
- PREGNANCY/BREAST FEEDING: Contact Drug Information for most recent information.
- Hypercalciuria, calcium renal calculi, history of renal calculi, sarcoidosis.
- Cardiac impairment, ventricular fibrillation during cardiac resuscitation.
- Digitalis toxicity: due to increased risk of arrhythmias.
- Dehydration: increased risk of hypercalcemia.
- Acidosis, cor pulmonale, renal and respiratory disease; calcium chloride is acidifying therefore calcium gluconate may be preferred.
- Digoxin: may increase risk of arrhythmias. ECG monitoring is recommended.
- 1 g over 3 minutes repeat x1 in 10 minutes if indications still present.
- Cardiac arrest: 20mg/kg (maximum single dose of 1g) over 3 minutes repeat x 1 in 10 minutes if indications still present.
- Non-arrest: 10mg/kg (maximum single dose of 1g) over 15 minutes repeat x 1 in 10 minutes if indications still present.
Ensure the line is well flushed between doses of Calcium and Bicarbonate to avoid precipitation