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Relieves pain by stimulating opiate receptors in CNS.
Onset of action:
Parenterally 15 minutes
Longer than 5 hours.
Relief of moderate to severe pain in opioid-tolerant patients.
Known hypersensitivity to hydromorphone or any ingredient in the formulation.
Respiratory depression in unmonitored settings or in the absence of resuscitative equipment.
Acute or severe asthma or hypercarbia.
Assess pain type and intensity prior to administration.
Assess efficacy of pain relief shortly after administration.
Assess respiratory rate, heart rate, and BP frequently.
Closely monitor for respiratory depression and CNS effects in elderly patients and patients with renal and/or hepatic impairment.
Cardiovascular hemodynamic anomalies.
CNS effects (depression, agitation).
0.02 mg/kg max dose 0.1 mg
Age: < 55 years: 1 - 2 mg IV ( .02/mg/kg) then 0.5 mg IV q5 min to 4 mg max.
Age: > 55 years: 0.5 - 1 mg IV then 0.5 mg IV q 5 min to 2 mg max.
6 - 12 years of age: 0.015 mg/kg q4–6 min prn
Children >12 years of age: 0.1 - 0.4 mg IV q4-6h